# What are the side effects of targeted therapy? Source: https://oncologyistanbul.com/answers/side-effects-of-targeted-therapy Last updated: 2026-07-13 Targeted therapy's side effects depend on the specific type of targeted therapy you receive and how your body reacts to it, according to the U.S. National Cancer Institute (NCI). The most common side effects may include diarrhea and liver problems. Other effects can include problems with blood clotting and wound healing, high blood pressure, fatigue, mouth sores, nail changes, loss of hair color, and skin problems such as rash or dry skin. NCI notes there are medicines for many of these side effects, and that most side effects of targeted therapy go away after treatment ends. This is general information, not personal medical advice. ## Verify at - [Targeted Therapy to Treat Cancer](https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies) — National Cancer Institute (NCI) (checked 2026-07-12) Related: [Targeted therapy, in depth](https://oncologyistanbul.com/treatments/targeted-therapy)