# What is a clinical trial in cancer, and is it safe to join one? Source: https://oncologyistanbul.com/answers/what-is-a-cancer-clinical-trial Last updated: 2026-07-12 According to the U.S. National Cancer Institute (NCI), a clinical trial is a type of research study that tests how well new medical approaches work in people. NCI explains that these studies test new methods of screening, prevention, diagnosis, or treatment of a disease, and that cancer clinical trials study new ways to find, prevent, and treat cancer. On the question of safety, NCI describes informed consent as a process in which patients are given important information — including the possible risks and benefits — about a clinical trial, to help them decide whether they want to take part; patients are also given any new information that might affect their decision to continue. In other words, whether to join is an informed decision you make with that information in hand. Whether a particular trial is right for you depends on your situation, so discuss the potential benefits and risks with your own oncology team. This is general information, not personal medical advice. ## Verify at - [NCI Dictionary — clinical trial](https://www.cancer.gov/publications/dictionaries/cancer-terms/def/clinical-trial) — National Cancer Institute (NCI) (checked 2026-07-12) - [What Are Cancer Clinical Trials?](https://www.cancer.gov/about-cancer/treatment/clinical-trials/what-are-trials) — National Cancer Institute (NCI) (checked 2026-07-12) - [NCI Dictionary — informed consent](https://www.cancer.gov/publications/dictionaries/cancer-terms/def/informed-consent) — National Cancer Institute (NCI) (checked 2026-07-12) Related: [The free 72-hour second opinion](https://oncologyistanbul.com/second-opinion)