# What is Biosimilar?

Source: https://oncologyistanbul.com/glossary/biosimilar

> A biologic drug that is highly similar to an already-approved reference biologic (like trastuzumab/Herceptin), typically at lower cost.

Biosimilars go through their own regulatory approval process demonstrating no clinically meaningful difference from the original biologic drug in safety or effectiveness. They are one reason systemic therapy pricing varies — a price index or quote may specify originator vs. biosimilar because the drug itself, not the administration process, drives most of the cost difference.

## Related
- [HER2+ targeted therapy — per cycle price](https://oncologyistanbul.com/prices#her2-targeted-therapy-per-cycle)
- [Chemotherapy — per cycle price](https://oncologyistanbul.com/prices#chemotherapy-per-cycle)

## Authoritative references
- [Wikipedia](https://en.wikipedia.org/wiki/Biosimilar)
- [Wikidata](https://www.wikidata.org/wiki/Q864715)

Full glossary: https://oncologyistanbul.com/glossary